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艾美捷科技代理Microbs品牌全系列产品


Microbs是一家处于科技前沿的创新企业,专注于微生物检测与质量控制领域的研发与服务。Microbs的核心技术——IAN®超快速微生物检测方法,是公司在微生物检测领域的重大突破。这一技术巧妙融合固相细胞术与人工智能,颠覆了传统微生物检测耗时长的局限。以往需要数天的检测流程,如今借助IAN®,仅需15分钟就能准确计数细菌、酵母菌和霉菌,极大地提高了检测效率,为微生物QC实验室的生产力提升带来了革命性变化。

具体介绍一下优势:

● IAN®全自动解决方案:操作简便,无需专业知识,即可实现定性和定量检测,并给出客观结果,无需额外解释。这一特性使得微生物检测更加普及化和便捷化,降低了检测门槛,让更多企业和机构能够轻松开展微生物检测工作。

● TVC-CAP总菌群分析产品:无需管理多个耗材,让检测流程更加简化。它适用于液体基质,能够检测总需氧和厌氧菌群,LOD(检测限)达到1个微生物/样品,具备出色的可追溯性和数据完整性,符合21 CFR第11部分的要求。

● 部门广泛:用于制造业可助优化流程、缩短交货时间、提高生产能力;在质量管控方面可以降低质量成本,实现无缺陷、无召回的目标;在实验室里,实现更快的批次发布,推动检测自动化并确保可追溯性;在供应链环节,减少库存,节省库存成本,减少安全库存和所需的存储区域。

● 全过程应用:在生物负荷测试中严控中间产品、原材料及工艺用水质量;无菌测试保障产品无菌性;环境控制全方位监测拭子、人员与空气;不合格调查能快速溯源污染,为各行业提供全流程微生物检测与质控支持。


产品信息描述
A fully automated solutionTo boost productivity in your microbial QC lab, Microbs is launching IAN®, an Ultra Rapid Microbiological Method allowing an accurate enumeration of bacteria, yeast and mold within minutes,


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KORD-Valmark.png

Kord-Valmark隶属于Bioplast Manufacturing公司,是专业化的培养皿生产商。

 

Kord-Valmark Labware Products by Bioplast Manufacturing, L.L.C. is a leading manufacturer of quality petri dishes. Our technical knowledge, experience and manufacturing capabilities – along with our superior mold design, precise process control and rigorous quality programs – allow us to manufacture the highest-quality products. Kord-Valmark’s disposable dishes provide unrivaled consistency, ease of use and exceptional value.

 

Kord-Valmark公司主要产品:

(1)Stackable Petri Dishes

Stackable polystyrene petri dishes are recommended for standard microbiology and general laboratory use

The stackable lid design ensures stability

Optically clear top and bottom viewing surfaces

Consistent flatness allows for even media distribution

Available in 3 sizes: 60 x 15 mm, 100 x 15 mm, and 100 x 25 mm

(2)Automation Petri Dishes

Automation and Slippable polystyrene petri dishes are recommended for standard microbiology and general laboratory use

Slippable lids provide a semi-stacking feature for hand use, while ensuring ease of use in automated equipment

Automation lids have no rim, ensuring ease of use in automated equipment

Select products are available with Side Arrows and/or ISO Mark Targets

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艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com

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AllerMAbs.jpg

艾乐美生物科技有限公司(AllerMAbs Co., Ltd.)成立于2015年,是台湾一家专注于生产高亲和力、高纯度并具有过敏原特异性的嵌合人类IgE单克隆抗体的生物公司。公司创办人团队在科研过程中发现市面上缺乏多样的IgE单克隆抗体,特別是具有过敏原特异性的人IgE 单抗。如果能制备出这种抗体,将有助于IgE 相关领域的研究工作。因此,AllerMAbs公司团队开始思考与研究利用基因克隆动物来制造人类 IgE 抗体的可行性,经过数年的努力于 2014年开发出人类IgE 抗体基因嵌入小鼠,通过杂交瘤技术 (Hybridoma technology),成功地研制出分泌嵌合人类IgE 单抗的 IgE 杂交瘤与纯化 IgE 抗体。经测试,此种嵌合人类IgE 单抗的物化性质与对免疫细胞的活性,皆与人类IgE 抗体一致,研究成果于2015 年发表在国际学术期刊上。

 

AllerMAbs的产品解决了目前人类IgE抗体不易制备的问题,让嵌合人类IgE抗体可以成为人类IgE抗体的替代品,并提供一个更稳定、更符合血清IgE检测系统的校正品,让临床血清IgE的检测结果更加准确与可靠。

 

其利用动物基因转殖技术,将组成人类IgE抗体分子的ε重链(Heavy chain)和κ轻链(Light chain)的编码基因(Encoding genes),分別嵌入(Knock-in)小鼠胚胎干细胞(Embryonic stem cells, ES cells)的γ1重链和κ轻链基因的位置,接着把胚胎干细胞分別植入孕母鼠体内,并将其带有嵌入基因之成鼠交互配种,最后得到带有人类IgE抗体重链和轻链基因的基因嵌入小鼠(HεκKI mice),且体内能制造完整的嵌合人类IgE抗体分子。

 

技术优势

容易制备IgE杂交瘤与IgE单抗

过敏原特异性

良好的亲和力与专一性

高纯度与高稳定性

可结合至嗜碱性粒细胞上的IgE受体与刺激細胞

可大量生产与高浓度制备

非人类血液来源(相较于血清IgE抗体)

适合用作检测用的校正品

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Genway Biotech.jpg

GenWay公司是为了探索和开发人类蛋白组而成立的。公司的总任务就是用基因特异性抗体來筛选和鉴定新蛋白、其功能及其编码基因,旨在成为以抗体介导的蛋白组研发的领域先锋。基因纬公司已成功地发展出一套有自己知识产权的、新穎、高效、低耗、高筛选通量的鉴定方法――抗体介导的蛋白和基因鉴定。公司提供大量的高质量的蛋白和相应的鸡抗体产品,是蛋白质组学研究的重要工具和有力助手。

 

As a leading protein and antibody solutions provider, GenWay has a proprietary technology platform and an international network to provide our clients with solutions and applications for proteins, antibodies, assays, and cell lines. We specialize in recombinant proteins and domain-specific IgY (chicken) antibodies and their applications, such as Seppro® products and difficult-to-express proteins. GenWay’s technology and expertise make high-quality protein antigens that enable production of high-quality antibodies and related applications.

 

GenWay Biotech的主要产品包括:

Proteins

Antibodies

ELISA Kits

Secondary Antibodies

Reagents

Peptides

Molecular Biology Products

Active Proteins

Enzymatic Assays

PCR Kits

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更多详情请联系 

艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com

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Zymo Research.jpg

Zymo Research公司位于美国加州Orange County,创建于上世纪90年代初,主要研发和生产生物实验室使用的各种试剂、耗材、仪器。其DNA提取试剂盒系列产品以“快速、简便、超纯”的特点在众多生物科技产品中脱颖而出,独占鳌头。已经形成了覆盖美、英、德、法、日、韩等50多个国家的销售网络,销售额快速增长。使用其产品的实验论文在各种权威性科技期刊(NATURE 自然、PNAS 美国科学院院刊、StemCells 干细胞、Nucleic Acids Res核酸研究等)上发表。

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艾美捷科技代理Zymo Research全系列产品,产品列表如下:


产品名称产品编号
Quick-DNA  Miniprep Plus KitD4068T / D4068 / D4069
Quick-DNA MiniprepD3024 / D3025
Quick-DNA Microprep KitD3020 / D3021
Quick-DNA 96 KitD3010 / D3011 / D3012
Quick-DNA Microprep Plus KitD4074
Quick-DNA Midiprep Plus KitD4075
Quick-DNA Magbead Plus KitD4081 / D4082
Quick-DNA  96 Plus KitD4070 / D4071
ZymoPURE II Plasmid Midiprep KitD4200 / D4201
ZymoPURE II Plasmid Maxiprep KitD4202 / D4203
ZymoPURE Plasmid Miniprep KitD4208T / D4209 / D4210 / D4211 / D4212
ZymoPURE - Express Plasmid Midiprep KitD4213
ZymoPURE II Plasmid Gigaprep KitD4204
DNA Clean & Concentrator-5D4003T / D4003 / D4013 / D4004 / D4014
DNA Clean & Concentrator-25D4033 / D4005 / D4034 / D4006
DNA Clean & Concentrator-100D4029 / D4030
ZR-96 DNA Clean & Concentrator-5 (Deep Well)D4023 / D4024
ZR-96 DNA Clean-Up KitD4017 / D4018
DNA Clean & Concentrator-500D4031 / D4032
ZymoBIOMICS DNA Miniprep KitD4300T / D4304 / D4300
ZymoBIOMICS DNA Microprep KitD4305 / D4301
ZymoBIOMICS 96 MagBead DNA KitD4306 / D4302 / D4308
ZymoBIOMICS 96 DNA KitD4307 / D4303 / D4309
Zymoclean Gel DNA Recovery KitD4001T / D4001 / D4007 / D4002 / D4008
Zymoclean Large Fragment DNA RecoveryD4045 / D4046
ZR-96 Zymoclean Gel DNA Recovery KitD4021 / D4022
Zyppy Plasmid Miniprep KitD4036 / D4019 / D4020 / D4037
Zyppy-96 Plasmid KitD4041 / D4042 / D4043
Zyppy-96 Plasmid MagBead MiniprepD4100 / D4101 / D4102
Genomic DNA Clean & Concentrator-10D4010 / D4011
Genomic DNA Clean & Concentrator-25D4064 / D4065
ZR-96 Genomic DNA Clean & Concentrator-5 KitD4066 / D4067
Quick-DNA Fecal/Soil Microbe Miniprep KitD6010
Quick-DNA Fecal/Soil Microbe MicroprepD6012
Quick-DNA Fecal/Soil Microbe 96 KitD6011
Quick-DNA Fecal/Soil Microbe 96 Magbead KitD6011-FM / D6010-FM / D6012-FM
Quick-DNA Fecal/Soil Microbe Midiprep KitD6110
Quick-DNA Fungal/Bacterial Miniprep KitD6005
Quick-DNA Fungal/Bacterial Microprep KitD6007
Quick-DNA Fungal/Bacterial 96 KitD6006
Quick-DNA Fungal/Bacterial Midiprep KitD6105
OneStep PCR Inhibitor Removal KitD6030 / D6035
Select-a-Size DNA Clean & Concentrator MagBead KitD4084 / D4085
Select-a-Size DNA Clean & Concentrator KitD4080
Quick-DNA Plant/Seed Miniprep KitD6020
Quick-DNA Plant/Seed 96 KitD6021
Quick-DNA/RNA Miniprep Plus KitD7003T / D7003
Quick-DNA/RNA Microprep Plus KitD7005T / D7005
Quick-DNA/RNA MiniprepD7001
Quick-DNA/RNA MagBeadR2130 / R2131
Zymoprep Yeast Plasmid Miniprep IID2004
Zymoprep Yeast Plasmid Miniprep ID2001
Zymoprep-96 Yeast Plasmid MiniprepD2005 / D2006 / D2007
Quick-DNA Viral KitD3015 / D3016
Quick-DNA Viral 96 KitD3017 / D3018
Quick-DNA Tissue/Insect Microprep KitD6015
Quick-DNA Tissue/Insect Miniprep KitD6016
Quick-DNA Tissue/Insect 96 KitD6017
ZR DNA Sequencing Clean-Up KitD4050 / D4051
ZR-96 DNA Sequencing Clean-up KitD4052 / D4053
Oligo Clean & ConcentratorD4060 / D4061
ZR-96 Oligo Clean & ConcentratorD4062 / D4063
Femto Bacterial DNA Quantification KitE2006
Femto Fungal DNA Quantification KitE2007
Femto Human DNA Quantification KitE2005
Direct-zol RNA Miniprep KitsR2050 / R2051 / R2052 / R2053
Direct-zol RNA Microprep KitsR2060 / R2061 / R2062 / R2063
Direct-zol RNA Miniprep Plus KitsR2070T / R2070 / R2071 / R2072 / R2073
Direct-zol-96 RNA KitsR2054 / R2055 / R2056 / R2057
Direct-zol-96 MagBead RNAR2100 / R2101 / R2102 / R2103
Direct-zol DNA/RNA MiniprepR2080T / R2080 / R2081
Quick-RNA Miniprep KitR1054 / R1055
Quick-RNA Microprep KitR1050 / R1051
Quick-RNA Miniprep Plus KitR1057T / R1057 / R1058
Quick-RNA Midiprep KitR1056
Quick-RNA 96 KitR1052 / R1053
Quick-RNA MagBeadR2132 / R2133
RNA Clean & Concentrator-5R1015 / R1013 / R1016 / R1014
RNA Clean & Concentrator-25R1017 / R1018
RNA Clean & Concentrator-100R1019
RNA Clean & Concentrator MagBeadR1081 / R1082
RNA Clean & Concentrator-96R1080
Quick-RNA Viral KitR1034 / R1034-E / R1035 / R1035-E
Quick-RNA Viral 96 KitR1040 / R1040-E / R1041 / R1041-E
Quick-RNA Fungal/Bacterial Miniprep KitR2014
Quick-RNA Fungal/Bacterial Microprep KitR2010
Quick-DNA/RNA Viral MagBeadR2140 / R2140-E / R2141 / R2141-E
Quick-DNA/RNA Viral 96 KitD7022 / D7023
Quick-DNA/RNA Viral KitD7020 / D7021
Proteinase K w/ Storage Buffer SetD3001-2-5 / D3001-2-20 / D3001-2-60 / D3001-2-125
Quick-DNA/RNA Pathogen MiniprepR1042 / R1043
Quick-DNA/RNA Pathogen MagBeadR2145 / R2146
Oligo Clean & ConcentratorD4060 / D4061
ZR-96 Oligo Clean & ConcentratorD4062 / D4063
Quick-RNA Plant KitR2024
Quick-RNA Fecal/Soil Microbe Microprep KitR2040
Quick-RNA Tissue/Insect KitR2030
Quick-RNA Whole BloodR1201
Quick-RNA FFPE MiniprepR1008
Quick-cfRNA Serum & Plasma KitR1059
ZR Urine RNA Isolation KitR1038 / R1039
Pinpoint Slide RNA Isolation SystemR1003 / R1007
Quick-DNA/RNA FFPE Miniprep KitR1009
Zymoclean Gel RNA Recovery KitR1011
ZR small-RNA  PAGE Recovery KitR1070
Oligo Clean & Concentrator KitsDNA
YeaStar RNA KitR1002
OneStep PCR Inhibitor Removal KitD6030
Zymo-Seq WGBS Library KitD5465
Pico Methyl-Seq Library Prep KitD5455 / D5456
Zymo-Seq RRBS Library KitD5460 / D5461
Zymo-Seq RiboFree Total RNA KitR3000 / R3003
Zymo-Seq RiboFree Universal cDNA KitR3001
Human Methylated & Non-methylated DNA SetD5014 / D5014-1 / D5014-2
5-mC DNA ELISA KitD5325 / D5326
OneStep qMethyl-PCR KitD5310 / D5311
Quest 5-hmC DNA ELISA KitD5425 / D5426
RRHP 5-hmC Library Prep KitD5450 / D5451
ZymoTaq PreMixE2003 / E2004
ZymoTaq DNA PolymeraseE2001 / E2002
ZymoTaq qPCR PremixE2054 / E2055
Zymo-Spin ChIP KitD5209 / D5210
ChIP DNA Clean & ConcentratorD5201 / D5205
ZR-96 ChIP DNA Clean & ConcentratorD5206 / D5207
EZ Nucleosomal DNA Prep KitD5220
dsDNA Shearase PlusE2018-200 / E2018-50
Methylated-DNA IP KitD5101
Anti-5-Methylcytosine Monoclonal Antibody (Clone 7D21)A3002-15 / A3002-200 / A3002-30 / A3002-50
Anti-5-Hydroxymethylcytosine Polyclonal AntibodyA4001-200 / A4001-25 / A4001-50
Universal Methylated DNA StandardD5011 / D5012
Bisulfite-Converted Universal Methylated Human DNA StandardD5015
Human Methylated & Non-Methylated (WGA) DNA SetD5013 / D5013-1 / D5013-2
5-Methylcytosine & 5-Hydroxymethylcytosine DNA Standard SetD5405
E. coli Non-Methylated Genomic DNAD5016
Methylated & Non-methylated pUC19 DNA SetD5017
Human Matched DNA SetD5018 / D5018-1 / D5018-2
Mouse 5-hmC & 5-mC DNA SetD5019 / D5019-1 / D5019-2 / D5019-3 / D5019-4
CpG Methylase (M. Sssl)E2010 / E2011
5-hmC GlucosyltransferaseE2026 / E2027
Atlantis dsDNaseE2030
DNA DegradaseE2016 / E2017
5-Methyl DctpD1035
5-Methylcytosine dNTP MixD1030
dNTP MixD1000-1 / D1000
dCTPD1020
dATPD1005
dTTPD1010
dGTPD1015
EZ DNA Methylation-Direct KitD5020 / D5021
EZ-96 DNA Methylation-Direct KitD5022 / D5023
EZ-96 DNA Methylation-Direct MagPrepD5044 / D5045
 EZ DNA Methylation KitD5001
 EZ DNA Methylation KitD5002
EZ-96 DNA Methylation KitD5003
EZ-97 DNA Methylation KitD5004
EZ-96 DNA Methylation MagPrepD5040
EZ-97 DNA Methylation MagPrepD5041
EZ DNA Methylation-GoldD5005
EZ DNA Methylation-GoldD5006
EZ-96 DNA Methylation-Gold KitD5007
EZ-97 DNA Methylation-Gold KitD5008
 EZ-96 DNA Methylation-Gold MagPrepD5042
 EZ-97 DNA Methylation-Gold MagPrepD5043
EZ DNA Methylation-Startup KitD5024
EZ DNA Methylation KitD5001
EZ DNA Methylation KitD5002
EZ-96 DNA Methylation KitD5003
EZ-97 DNA Methylation KitD5004
EZ-96 DNA Methylation MagPrepD5040
EZ-97 DNA Methylation MagPrepD5041
ZymoBIOMICS DNA Miniprep KitD4300T / D4304 / D4300
ZymoBIOMICS DNA Microprep KitD4305 / D4301
ZymoBIOMICS 96 MagBead DNA KitD4306 / D4302 / D4308
ZymoBIOMICS 96 DNA KitD4307 / D4303 / D4309
ZymoBIOMICS Gut Microbiome StandardD6331
ZymoBIOMICS HMW DNA StandardD6322
ZymoBIOMICS Microbial Community DNA StandardD6305 / D6306
ZymoBIOMICS Microbial Community StandardD6300
ZymoBIOMICS Spike-in Control I (High Microbial Load)D6320 / D6320-10
ZymoBIOMICS Microbial Community DNA Standard II (Log Distribution)D6311
ZymoBIOMICS Microbial Community Standard II (Log Distribution)D6310
ZymoBIOMICS Spike-in Control II (Low Microbial Load)D6321 / D6321-10
ZymoBIOMICS Fecal Reference with TruMatrix TechnologyD6323
Femto Bacterial DNA Quantification KitE2006
Femto Fungal DNA Quantification KitE2007
Femto Human DNA Quantification KitE2005
Quick-16S Plus NGS Library Prep Kit(V3-V4)D6420 / D6422
ZymoBIOMICS DNA/RNA Miniprep KitR2002
ZymoBIOMICS MagBead DNA/RNAR2135 / R2136
ZymoBIOMICS RNA Miniprep KitR2001
Mix & Go! E. coli Transformation Kit and Buffer SetT3001 / T3002
Mix & Go Competent CellsE. coli
XJ Autolysis E. coli strainsE. coli
Rattler Plating BeadsS1001 / S1001-5 / S1001-B
ZymoBrothM3015-100 / M3015-500
Dual Media SetM3011
Ampicillin Sodium SolutionA1001-25 / A1001-5
Kanamycin Sulfate SolutionA1003-25 / A1003-5
Chloramphenicol SolutionA1002-25 / A1002-5
X-GAL (5-bromo-4-chloro-3-indolyl β-D-galactopyranoside)X1001-25 / X1001-5
500x L-Arabinose SolutionA2001-1 / A2001-10
Tetracycline Hydrochloride Solution - Reagent GradeA1004-25 / A1004-5
Mix & Go! Competent Cells - DH5 AlphaT3007 / T3009 / T3010
Mix & Go! Competent Cells-JM109T3003 / T3005
Mix & Go! XJb (DE3) Autolysis Competent CellsT3051
Mix & Go! Competent Cells-Zymo 10BT3019 / T3020
Mix & Go! Competent Cells-TG1T3017
Mix & Go! Competent Cells-HB101T3011 / T3013
Mix & Go! XJa (DE3) Autolysis Competent CellsT3031
Mix & Go! XJb Autolysis Competent CellsT3041
Mix & Go! XJa Autolysis Competent CellsT3021
Mix & Go! XJb (DE3) Autolysis Competent CellsT3051
XJb (DE3) Autolysis Glycerol StockT5051
Mix & Go! XJa (DE3) Autolysis Competent CellsT3031
Mix & Go! XJb Autolysis Competent CellsT3041
XJb Autolysis Glycerol StockT5041
XJa (DE3) Autolysis Glycerol StockT5031
XJa Autolysis Glycerol StockT5021
Mix & Go! XJa Autolysis Competent CellsT3021
Zymoprep Yeast Plasmid Miniprep KitsYeast
Quick-DNA Fungal/Bacterial KitsDNA
ZymolyaseE1004 / E1005 / E1006
5-Fluoroorotic Acid (5-FOA)F9001-1 / F9001-5 / F9003
YeaStar RNA KitR1002
Frozen-EZ Yeast Transformation II KitT2001
Frozen-EZ Yeast SolutionT2002 / T2003 / T2004
YeaStar Genomic DNA KitD2002
YPD PlusY1003-100 / Y1003-50
Zymoprep Yeast Plasmid Miniprep ID2001
Zymoprep Yeast Plasmid Miniprep IID2004
Zymoprep-96 Yeast Plasmid MiniprepD2007
Quick-DNA Fungal/Bacterial Microprep KitD6007
Quick-DNA Fungal/Bacterial Miniprep KitD6005
Quick-DNA Fungal/Bacterial Midiprep KitD6105
Quick-DNA Fungal/Bacterial 96 KitD6006
Zymoprep Yeast Plasmid Miniprep ID2001
Zymoprep Yeast Plasmid Miniprep IID2004
Zymoprep-96 Yeast Plasmid MiniprepD2007
Quick-DNA Fungal/Bacterial Microprep KitD6007
Quick-DNA Fungal/Bacterial Miniprep KitD6005
Quick-DNA Fungal/Bacterial Midiprep KitD6105
Quick-DNA Fungal/Bacterial 96 KitD6006
XJ Autolysis E. coli strainsE. coli
His-Spin Protein MiniprepP2001 / P2002
Yeast Protein KitY1002
Strep-Spin Protein Miniprep KitP2004 / P2005
ZymolyaseE1004 / E1005 / E1006
DNase I SetE1010
ZymoTaq PolymeraseBuffers
DNA Degradase PlusE2020 / E2021
MBP-Spin Protein Miniprep KitP2006 / P2007
Dual Media SetM3011
dsDNA Shearase PlusE2018-200 / E2018-50
RNase AE1008-24 / E1008-30 / E1008-8
CpG Methylase (M. Sssl)E2010 / E2011
Atlantis dsDNaseE2030
Proteinase K w/ Storage Buffer SetD3001-2-20 / D3001-2-5
5-hmC GlucosyltransferaseE2026 / E2027
Micrococcal NucleaseD5220-1
DNA DegradaseE2016 / E2017
Mix & Go! XJb (DE3) Autolysis Competent CellsT3051
XJb (DE3) Autolysis Glycerol StockT5051
Mix & Go! XJa (DE3) Autolysis Competent CellsT3031
Mix & Go! XJb Autolysis Competent CellsT3041
XJb Autolysis Glycerol StockT5041
XJa (DE3) Autolysis Glycerol StockT5031
XJa Autolysis Glycerol StockT5021
Mix & Go! XJa Autolysis Competent CellsT3021
ZymoTaq PreMixE2003 / E2004
ZymoTaq DNA PolymeraseE2001 / E2002
ZymoTaq qPCR PremixE2054 / E2055


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Dendritics公司主要关注人类树突状细胞,希望找到能够促使CD34+造血前体细胞转化为树突状细胞(在GM-CSF和TNF-alpha存在的情况下)的细胞因子。在1992-2005年间,大量的研究使得研究者对人类树突状细胞的产生、细胞通路、C-type凝集素受体的功能及Toll-like受体的活性有了更深的理解。

 

DENDRITICS was started in 2005 by former members of SCHERING PLOUGH Laboratory for Immunological Research (LIR) in Dardilly, France. From their long experience at LIR, the team members of DENDRITICS have gathered complementary scientific and technological knowledge in different areas of immunology. The initial focus of LIR was in the biology of B lymphocytes, elaboration of human monoclonal antibodies, and in cytokine discovery (IL-3, IL-4, IL-7, IL-10, IL-17, GM-CSF) together with our colleagues of DNAX Research Institute in Palo Alto, California.

 

Our interest in cytokines led to the finding that human dendritic cells (DCs) could be generated in vitro from CD34+ hematopoietic progenitors cultured in the presence of GM-CSF and TNF-alpha.

 

The period from 1992 to 2005 saw the specialization of LIR in DC biology and was fuelled by a large-scale effort to discover and study the function of genes specifically expressed by these cells. This program led to a number of findings that contributed in particular to understanding the heterogeneity of DCs, the pathways regulating DC migration, the function of C-type lectin receptors in DCs and the activity of Toll-like receptors in DCs. Many novel genes were discovered through screening of cDNA libraries or through monoclonal antibodies raised against DCs.

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